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The aim of this study was to investigate the impact of decay data provided bythe newly developed stochastic atomic relaxation model BrIccEmis on dose pointkernels (DPKs - radial dose distribution around a unit point source) andS-values (absorbed dose per unit cumulated activity) of 14 Auger electron (AE)emitting radionuclides, namely 67Ga, 80mBr, 89Zr, 90Nb, 99mTc, 111In, 117mSn,119Sb, 123I, 124I, 125I, 135La, 195mPt and 201Tl. Radiation spectra were basedon the nuclear decay data from the medical internal radiation dose (MIRD)RADTABS program and the BrIccEmis code, assuming both an isolated-atom andcondensed-phase approach. DPKs were simulated with the PENELOPE Monte Carlo(MC) code using event-by-event electron and photon transport. S-values forconcentric spherical cells of various sizes were derived from these DPKS usingappropriate geometric reduction factors. The number of Auger and Coster-Kronig(CK) electrons and x-ray photons released per nuclear decay (yield) fromMIRD-RADTABS were consistently higher than those calculated using BrIccEmis.DPKs for the electron spectra from BrIccEmis were considerably different fromMIRD-RADTABS in the first few hundred nanometres from a point source where mostof the Auger electrons are stopped. S-values were, however, not significantlyimpacted as the differences in DPKS in the sub-micrometre dimension werequickly diminished in larger dimensions. Overestimation in the total AE energyoutput by MIRD-RADTABS leads to higher predicted energy deposition by AEemitting radionuclides, especially in the immediate vicinity of the decayingradionuclides. This should be taken into account when MIRD-RADTABS data areused to simulate biological damage at nanoscale dimensions.

Absorbed dose evaluation of Auger electron-emitting radionuclides: impact of input decay spectra on dose point kernels and S-values