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We extend the analysis of \cite{Bezrukov:2008ej} of the Standard Model Higgsinflation accounting for two-loop radiative corrections to the effectivepotential. As was expected, higher loop effects result in some modification ofthe interval for allowed Higgs masses m_min<m_H<m_max, which somewhat exceedsthe region in which the Standard Model can be considered as a viable effectivefield theory all the way up to the Planck scale. The dependence of the indexn_s of scalar perturbations on the Higgs mass is computed in two differentrenormalization procedures, associated with the Einstein (I) and Jordan (II)frames. In the procedure I the predictions of the spectral index of scalarfluctuations and of the tensor-to-scalar ratio practically do not depend on theHiggs mass within the admitted region and are equal to n_s=0.97 and r=0.0034respectively. In the procedure II the index n_s acquires the visible dependenceon the Higgs mass and and goes out of the admitted interval at m_H below m_min.We compare our findings with the results of \cite{DeSimone:2008ei}.

Standard Model Higgs boson mass from inflation: two loop analysis