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This paper reviews the usual techniques for producing YBCO-typesingle-domains and the microstructure of the as-obtained samples. The problemsof seed dissolution and parasite nucleations are discussed in details.Formation of microstructural defects, such as pores and cracks, are examined.An important part of this review is devoted to the study of the influence ofRE-211 particles [RE2BaCuO5 where RE denotes Y, Yb, Nd, Sm, Dy, Gd, Eu or amixture of them. Generally Nd4Ba2Cu2O10 is preferred to Nd2BaCuO5] on themicrostructure and properties of RE-Ba-Cu-O single-domains. Trapping/Pushingtheory is described in order to explain the spatial distribution of RE-211particles in the RE-123 [(RE)Ba2Cu3O7-d] monoliths. Formation of RE-211-freeregions is discussed. Different ways to limit the RE-211 coarsening arereviewed. Microstructural defects in the RE-123 matrix caused by the RE-211particles are presented. It is also shown that RE-211 particles play asignificant role on the mechanical properties of single-domain samples. Wefinish this review by discussing the Infiltration and Growth process as a goodtechnique to control the microstructure.Comment: review paper to be published in Supercond. Sci. Technol.; 19 figures;  137 references; 37 page

From RE-211 to RE-123. How to control the final microstructure of superconducting single-domains