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We probe the systematic uncertainties from 113 Type Ia supernovae (SNIa) inthe Pan-STARRS1 (PS1) sample along with 197 SN Ia from a combination oflow-redshift surveys. The companion paper by Rest et al. (2013) describes thephotometric measurements and cosmological inferences from the PS1 sample. Thelargest systematic uncertainty stems from the photometric calibration of thePS1 and low-z samples. We increase the sample of observed Calspec standardsfrom 7 to 10 used to define the PS1 calibration system. The PS1 and SDSS-IIcalibration systems are compared and discrepancies up to ~0.02 mag arerecovered. We find uncertainties in the proper way to treat intrinsic colorsand reddening produce differences in the recovered value of w up to 3%. Weestimate masses of host galaxies of PS1 supernovae and detect an insignificantdifference in distance residuals of the full sample of 0.037\pm0.031 mag forhost galaxies with high and low masses. Assuming flatness in our analysis ofonly SNe measurements, we find $w = {-1.120^{+0.360}_{-0.206}\textrm{(Stat)}^{+0.269}_{-0.291}\textrm{(Sys)}}$. With additional constraints from BAO,CMB(Planck) and H0 measurements, we find $w = -1.166^{+0.072}_{-0.069}$ and$\Omega_M=0.280^{+0.013}_{-0.012}$ (statistical and systematic errors added inquadrature). Significance of the inconsistency with $w=-1$ depends on whetherwe use Planck or WMAP measurements of the CMB:$w_{\textrm{BAO+H0+SN+WMAP}}=-1.124^{+0.083}_{-0.065}$.

Systematic Uncertainties Associated with the Cosmological Analysis of the First Pan-STARRS1 Type Ia Supernova Sample