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MIRI (the Mid-Infrared Instrument for the James Webb Space Telescope (JWST))operates from 5 to 28.5 microns and combines over this range: 1.) unprecedentedsensitivity levels; 2.) sub-arcsec angular resolution; 3.) freedom fromatmospheric interference; 4.) the inherent stability of observing in space; and5.) a suite of versatile capabilities including imaging, low and mediumresolution spectroscopy (with an integral field unit), and coronagraphy. Weillustrate the potential uses of this unique combination of capabilities withvarious science examples: 1.) imaging exoplanets; 2.) transit and eclipsespectroscopy of exoplanets; 3.) probing the first stages of star and planetformation, including identifying bioactive molecules; 4.) determining starformation rates and mass growth as galaxies are assembled; and 5.)characterizing the youngest massive galaxies. This paper is the introduction toa series of ten covering all aspects of the instrument.

The Mid-Infrared Instrument for the James Webb Space Telescope I: Introduction