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Health care-associated, central venous catheter-related bloodstream infections (HA-BSIs) are a major cause of morbidity and mortality. Needleless connectors (NCs) are an important component of the intravenous system. NCs initially were introduced to reduce health care worker needlestick injuries, yet some of these NCs may increase HA-BSI risk.

Health Care–Associated Bloodstream Infections Associated with Negative‐ or Positive‐Pressure or Displacement Mechanical Valve Needleless Connectors