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Despite suppression of the human immunodeficiency virus type 1 (HIV-1) load by highly active antiretroviral therapy (HAART), recovery of CD4+ T cell counts can be impaired. We investigated whether this impairment may be associated with hyporesponsiveness of T cells to gamma-chain (gammac) cytokines known to influence T cell homeostasis.

the journal of infectious diseases (online. university of chicago press)/the journal of infectious diseases

Responsiveness of T Cells to Interleukin‐7 Is Associated with Higher CD4<sup>+</sup>T Cell Counts in HIV‐1–Positive Individuals with Highly Active Antiretroviral Therapy–Induced Viral Load Suppression

Responsiveness of T Cells to Interleukin‐7 Is Associated with Higher CD4+T Cell Counts in HIV‐1–Positive Individuals with Highly Active Antiretroviral Therapy–Induced Viral Load Suppression

Responsiveness of T Cells to Interleukin‐7 Is Associated with Higher CD4⁺T Cell Counts in HIV‐1–Positive Individuals with Highly Active Antiretroviral Therapy–Induced Viral Load Suppression