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In adult mammals and birds there is a great quantitative difference in the reticulo-endothelial system content of the bone marrow of central bones as compared with distal outlying bones. Experimental procedures reported in the accompanying communication effecting development and increase of hemopoiesis in inactive yellow marrow also effect a reticulo-endothelial cell increase.

AN INCREASE IN RETICULO-ENDOTHELIAL CELLS IN OUTLYING BONE MARROW CONSEQUENT UPON A LOCAL INCREASE IN TEMPERATURE