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Repeated parenteral injections by various routes in a series of twelve rabbits caused an increase of lymphocytes in the peripheral blood varying from 23 per cent to 139 per cent. It seems probable that the degree of response is conditioned upon the type of protein used. At autopsy the lymph nodes and spleen showed hyperplastic changes. The thymus did not participate in the hyperplasia.

THE INDUCTION OF LYMPHOCYTOSIS AND LYMPHATIC HYPERPLASIA BY MEANS OF PARENTERALLY ADMINISTERED PROTEIN