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A technique is described for total removal of the liver of the rabbit without circulatory difficulties as a result. The method requires a preliminary operation to induce a development of portal and caval collaterals. Rabbits deprived of the liver in this manner if given glucose live for varying periods up to 40 hours. Before death they show the same disturbances as do hepatectomized dogs. They die early, of hypoglycemia, unless provided with sugar.

TOTAL SURGICAL REMOVAL OF THE LIVER IN RABBITS