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1. Increase in circulatory rate caused by hard exercise has no power to dislocate nucleated red cells from the bone marrow either in normal, in anemic, in hyperplastic, or in anemic and hyperplastic animals. 2. In anemic and hyperplastic animals pseudocrises of nucleated red cells can be produced at certain periods by hard exercise, but careful analysis leads inevitably to the conclusion that the increase in these cells is merely a more accurate expression of circulatory content at the time of the procedure. 3. Section of the vasomotor nerves to the four limbs with consequent dilatation of the marrow vessels and increased blood flow through the tissue does not result in the freeing of nucleated red cells from the bone marrow.

THE FACTORS CONCERNED IN THE APPEARANCE OF NUCLEATED RED BLOOD CORPUSCLES IN THE PERIPHERAL BLOOD