English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

On September 5, 191o, an epidemic of distemper, also known as influenza or shipping fever, broke out among the horses of Squadron C of the National Guard of the State of New York. The symptoms, in brief, were a sudden onset with elevation of temperature of lO5 ° to lO6 ° F., marked weakness, constipation, partial or complete loss of appetite, and extreme depression. The pulse rose only slightly above normal, except in the last stages of the disease. The duration of the disease, on the average, was from seven to ten days. There were thirty-one cases in all, of which thirteen terminated fatally. The diagnosis of influenza or distemper was made. On December 2o, 19IO , I was consulted with the view of studying the bacteriology of the disease. Thinking that the mouse might be an important factor in the spread of the epidemic, I autopsied a number of mice that were found dead in ,the stable. Autopsy.-The peritoneums were hyperemic in spots and contained a small amount of viscid gelatinous fluid. All the organs were markedly congested, otherwise negative. Cultures from the blood and organs revealed a Gram-positive, spore-bearing, actively motile, non-encapsulated bacillus, which did not appear in chains, but singly and in pairs. Inoculation of this organism into mice, rats, guinea pigs, and rabbits proved non-fatal. I thus ruled out the anthrax bacillus as the causative agent. The micro6rganism isolated was a saprophyte. That the epidemic was due to a contagion was evident, and that the contagion was of a bacterial nature was probable. Accordingly I withdrew from the jugular vein ten cubic centimeters of blood and inoculated it on various media. The results were negative.

THE BACTERIOLOGY AND VACCINE THERAPY OF DISTEMPER IN HORSES