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1. Hypertrophy induced by the production of aortic insufficiency involves all the chambers of the heart. The greatest absolute increase in weight is in the left ventricle. The remaining segments, arranged in the order of decreasing increments are septum, right ventricle, and auricles. The greatest relative increase is also in the left ventricle, but the auricles show a relative hypertrophy greater than that of the septum or right ventricle. 2. The co-hypertrophy of the auricles is not due to an altered venous pressure, but results from an increased force of auricular systole. 3. The heart shows an increase in weight within one week after the production of aortic insufficiency. The increase in weight is due only in part to an increased water content.

AN EXPERIMENTAL CONTRIBUTION TO THE STUDY OF CARDIAC HYPERTROPHY