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.--In this paper are given the results of observations, which I have made, on the relation between the heart-weight and the body-weight in different animals. So far as I am aware, very little, if anything, has appeared on this subject in this country, although considerable work has been published on this and closely related subjects in Europe. For that reason I have thought it worth while to collect from previous investigators a few of the figures which seemed most interesting and have arranged them in ~abular form near the end of this communication. In the literature, we find numerous tabulations which give the weight, dimensions, etc., of the various organs of the body, and also the relation between the size of individual organs and the size of the body. These have been determined for man in the normal and in several pathological conditions. Vierordt ( I ) gives tables showing the weights and measurements of almost every organ of the body. Bergmann (2) gives the relation of the heart-weight to the body-weight in man and several species of animals. Parrot (3) published an extensive article upon this relation in fifty or more species of birds. Hasenfeld and Romberg, (4) W. Miiller (5) and Kfilbs (6) may be mentioned. Many of the normal ratios were determined in order to have controls for experiments upon the effects of exercise or valvular defects of the heart upon cardiac hypertrophy and related subjects. There are some variations between the figures of these investigators for an individual species, but for the most part they are fairly constant. The use of different methods may account for many of the differences. 1 Received for publication May 6, 19o8.

THE RATIO BETWEEN THE HEART-WEIGHT AND BODY-WEIGHT IN VARIOUS ANIMALS