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With Aβ, the danger lies within
Author(s) -
William A. Wells
Publication year - 2002
Publication title -
the journal of cell biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 5.414
H-Index - 380
eISSN - 1540-8140
pISSN - 0021-9525
DOI - 10.1083/jcb1563iti1
Subject(s) - biology , extracellular , intracellular , tunel assay , programmed cell death , in situ nick end labeling , disease , amyloid (mycology) , microbiology and biotechnology , neuroscience , apoptosis , pathology , biochemistry , botany , medicine
![Graphic][1] Intracellular injection of Aβ1–42 induces neuronal cell death and TUNEL staining (green).The most obvious symptom is not always the most relevant. In Alzheimer's disease (AD), for example, post-mortem brain analyses show large extracellular amyloid plaques of

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