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Plant lectins, because they bind to specific carbohydrate moieties, can be used to investigate the glyco-components of the cell surface. When considering the distribution, number, or mobility of lectin-binding sites, a distinction must be made between a natural distribution and a redistribution induced by binding with multivalent ligands (2, 4, 5, 8, 14, 15). In some cell types the induced redistribution results in the phenomenon of "capping." Taylor et al. (14), on the basis of immunofluorescent studies, introduced the term capping to refer to the progressive movement and clumping of receptor-ligand complexes (e.g. binding site-lectin complexes) to form an aggregate of these com-

VISUALIZATION OF CONCANAVALIN A-BINDING SITES WITH SCANNING ELECTRON MICROSCOPY