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We previously showed (5) that in double animals of Euplotes the two separate macronuclei begin D N A synthesis simultaneously, demonstrating that the cytoplasm plays a role in initiating DNA synthesis. By studying the timing of DNA synthesis in both the micronucleus and the macronucleus, we have obtained evidence that the initiation of D N A synthesis depends not only upon cytoplasmic conditions but also upon the properties of the particular nucleus.

COMPARISON BETWEEN THE TIMING OF MICRONUCLEAR AND MACRONUCLEAR DNA SYNTHESIS IN EUPLOTES EURYSTOMUS