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Cancer patients suffer severely from bodily damage due to malignant neoplasms and live a life of low quality, while the occurrence of adverse drug reactions (ADRs) worsens these conditions. Risk factors associated with ADRs have been long discussed in the literature, yet few studies considered prescriber-related risks. This study filled the gap by examining the ADR risk of prescriber-related factors from two dimensions: prescriber experience and prescriber continuity. We conducted a logistic regression analysis to investigate the effects. The data for analysis contained 34,474 inpatient admissions linked to 2,750,685 medication orders. We found that both experienced prescriber and prescriber continuity are related to lower ADR risk. Our results also revealed that the involvement of more experienced physicians in the prescribing process could mitigate the harmful effects of prescriber non-continuity on ADRs.

The impact of prescriber experience and continuity on adverse drug reactions in hospitalized cancer patients