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We have recently reported a correlation between the accumulation of specific T &gt; C and T &gt; G mutations and the chromosomal instability in cells of Barrett's esophagus (BE), which represents a premalignant condition of esophageal adenocarcinoma. Additionally, we identified seven marker genes that facilitate the distinction of individual BE stages by histopathological examination.

Barrett's esophagus stages: their correlation with SBS17-associated DNA mutations and the identification of histological marker genes