English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

This study aimed to evaluate the antidiabetic and antioxidant potentials of fractions from  Cassia siamea  and  Butea monosperma . The water, hexane, dichloromethane, and ethyl acetate fractions of tested plants was determined their bioactivities by hemolysis, antiglycation, alpha-glucosidase and dipeptidyl peptidase-IV (DPP-IV) inhibition, glucose uptake by yeast cells, DPPH radical scavenging, and total phenolic content determination assays. Non-hemolytic effects of all fractions were shown by &lt; 20% on RBCs. The best inhibition activities for AGE formation of water and hexane fractions from  C. siamea  were shown in IC 50  values (mg/mL) of 0.17 and 0.14, respectively. For  B. monosperma , the EtOAc fraction exhibited the best inhibitory effect with an IC 50  value of 0.10 mg/mL. The water and ethyl acetate fractions of  C. siamea  strongly inhibited α-glucosidase, and their IC 50  values were 0.16 mg/mL and 0.17 mg/mL, respectively. Ethyl acetate fractions of  B. monosperma  significantly inhibited α-glucosidase, with a respective IC 50  value of 0.14 mg/mL. DPP-IV inhibitory activities for water, hexane, and ethyl acetate fractions of  C. siamea  revealed with IC 50  values of 0.11, 0.09, and 0.18 mg/mL, respectively and those of  B. monosperma  were 0.23, 0.13, and 0.24 mg/mL, respectively. The glucose uptake effect observed in the water and ethyl acetate fractions of  B. monosperma  was better than that observed in the fractions of  C. siamea  at tested glucose concentrations (5-25 mM). In addition, all tested fractions were very active in antioxidant capacity. This study indicated that the water fraction of  C. siamea  and ethyl acetate fraction of  B. monosperma  exhibited the best antidiabetic potential with high antioxidant power.

journal of biologically active products from nature

In vitro  Investigation on Antidiabetic and Antioxidant Assessments of Partially Purified Fractions of  Cassia siamea  and  Butea monosperma : Indigenous Myanmar Medicinal Plant