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Bryophyllum pinnatum  is a well-known medicinal plant that has been used in many traditional systems of medicines. This includes treating fever, smallpox, otitis, cough, asthma, headache, convulsion, and general debility. The various secondary metabolites identified from  B. pinnatum  include steroids, flavonoids, terpenoids, fatty acid, bufadienolides, protein and peptides, vitamins, polysaccharide, and others. Numerous studies have also shown that extracts and purified compounds from  B. pinnatum  exert a wide spectrum of pharmacological effects  in vivo  and  in vitro . These include antimicrobial, anti-ulcer, antihypertensive, antileishmanial, anti-cancer, anti-diabetic, and immunomodulatory effects. This present paper presents a comprehensive review of the traditional uses, phytochemistry, and pharmacological studies on  B. pinnatum  over a period of thirty years with the aim of providing ready information that may trigger further research into the possible beneficial application of the plant. The review also includes some insight into the clinical uses and potential of  B. pinnatum .

A Review of the Traditional Uses, Phytochemistry and Pharmacology of Bryophyllum pinnatum (Lam.) (Crassulaceae)