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Background:  Allergic reactions in the oral cavity can be triggered by a wide range of common allergens, dental materials and medications that can cause oral and systemic clinical manifestations. Diverse symptoms and signs of allergic reactions in the oral cavity mimic other common diseases, making diagnosis difficult. Hence, early diagnosis and management are necessary to reduce the risk of serious complications. Types of articles reviewed:  This review was performed by compiling information available from various popular search engines on the internet, in textbooks and in bibliographic databases such as Google Scholar, PubMed (Medline) and Scopus. Results:  This article aims to enumerate various types of hypersensitivity reactions based on algorithmic approach. The duration, recurrent nature, morphology, location and systemic symptoms that are useful in evaluating etiology, signs and symptoms of allergic reactions in the oral cavity are discussed. Practical implications:  In general, a detailed history of the patient’s diet, drugs and systemic features is essential for correct diagnosis and management of their condition. This review updates the dentist to understand and enhance their knowledge for better diagnosis and treatment.

Allergic Manifestations in the Oral Cavity