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This study aimed to identify the factors affecting the quality of life (QOL) and functional status of patients with MDS. We reviewed the literature published in PUBMED over the past 30 years and searched for keywords such as ‘quality of life’ and ‘myelodysplastic syndromes’. By observing the influence of their symptoms, the possibility of improving patients’ QOL was considered by improving these related factors. Concurrently, the effects of related clinical treatments based on the unique disease characteristics of MDS on the patients’ QOL were examined, and lifestyle factors were considered in clinical practice, providing an important path to improve the QOL and functional status of patients with MDS. This review summarized several areas that can improve the quality of survival of MDS patients and discusses them in depth. Although the clinical benefits may be minimal, we still hope to improve patients’ daily life outcomes and enhance their quality of life at minimal cost. Also, we hope more researchers will focus on this area in the future to find more factors that may exist to supplement the limitations of these understanding and thinking, and to provide assistance in clinical work.

Quality of life considerations and management in patients with myelodysplastic syndrome