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Purpose: Whilst pre‐exercise ischaemic preconditioning (IPC) can improve lower‐body exercise performance, its impact on upper‐limb performance has received little attention. This study examines the influence of IPC on upper‐body exercise performance and oxygen uptake (V̇O 2 ) kinetics. Methods: Eleven recreationally‐active males (24 ± 2 years) completed an arm‐crank graded exercise test to exhaustion to determine the power outputs at the ventilatory thresholds (VT1 and VT2) and V̇O 2peak  (40.0 ± 7.4 ml·kg −1 ·min −1 ). Four main trials were conducted, two following IPC (4 × 5‐min, 220 mmHg contralateral upper‐limb occlusion), the other two following SHAM (4 × 5‐min, 20 mmHg). The first two trials consisted of a 15‐minute constant work rate and the last two time‐to‐exhaustion (TTE) arm‐crank tests at the power equivalents of 95% VT1 (LOW) and VT2 (HIGH), respectively. Pulmonary V̇O 2  kinetics, heart rate, blood‐lactate concentration, and rating of perceived exertion were recorded throughout exercise. Results: TTE during HIGH was longer following IPC than SHAM (459 ± 115 vs 395 ± 102 s,  p  = .004). Mean response time and change in V̇O 2  between 2‐min and end exercise (ΔV̇O 2 ) were not different between IPC and SHAM for arm‐cranking at both LOW (80.3 ± 19.0 vs 90.3 ± 23.5 s [ p  = .06], 457 ± 184 vs 443 ± 245 ml [ p  = .83]) and HIGH (96.6 ± 31.2 vs 92.1 ± 24.4 s [ p  = .65], 617 ± 321 vs 649 ± 230 ml [ p  = .74]). Heart rate, blood‐lactate concentration, and rating of perceived exertion did not differ between conditions (all  p  ≥. 05). Conclusion: TTE was longer following IPC during upper‐body exercise despite unchanged V̇O 2  kinetics.

Ischaemic preconditioning improves upper‐body endurance performance without altering V̇O 2 kinetics