English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Methamphetamine (METH) is a strong central nervous system stimulant that has toxic effects on the reproductive system. The aim of this study was to evaluate changes in gene and protein expression levels of CatSper1, 2, and oxidative stress after exposure to METH in the testis of mice. The mRNA and protein expression levels of CatSper1, 2 decreased in the experimental groups. The administration of METH caused a decrease of SOD and CAT activities and an increase in the MDA level. METH damaged the male reproductive system via the oxidative stress pathway and by reduction of CatSper1, 2 genes and protein expression. Mini-abstract: Administration of METH damaged the male reproductive system via the oxidative stress pathway and reduction of CatSper1, 2 genes and protein expression.

Down-regulation of CatSper 1 and CatSper 2 genes by methamphetamine