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Objective:  We reviewed our experience with congenital hepatic hemangiomas (CHH) to assess the effectiveness of our treatment strategies.  Methods:  Clinical and pathologic features of children with CHH were reviewed.  Results:  Twenty-two cases of CHH were collected, 17 were resected and 5 were followed until resolution. In 17 with alpha-feto-protein (AFP) levels, 9 were elevated with 5 decreasing to normal before surgery. In six with tumors under 3 cm, five regressed between 1 and 13 months, one required removal 5 years after initial diagnosis. Postoperative histopathology of 17 cases showed abnormal vascular hyperplasia without lobular architecture. CD34 was expressed in all tumors, glucose transporter 1(Glut1) was negative.  Conclusion:  If the tumor is less than 3 cm, AFP is normal and there are no obvious complications, the lesion can be followed with regular assessment imaging. Surgical resection is an option in tumors less than 3 cm which have not regressed over time.

Clinical and Pathological Features of Congenital Hepatic Hemangioma in Children: A Retrospective Analysis