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Six male patients with gout were treated with combined oral medication (febuxostat, 120 mg/d, and benzbromarone, 50 or 100 mg/d), aiming at a more rapid success of uric acid lowering treatment (ULT) compared to guideline suggestions. By combined oral medication in moderate dosage, the sUA was reduced to &lt;2 mg/dl in all cases. We conclude that, by the treatment schedule outlined, the majority of patients with gout can be cured within 1 – 2 years, with uricase treatment being necessary very rarely only.

Treating gout – can hypouricemia produced by moderate doses of combined oral treatment give early treatment success? Preliminary observations