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Phragmanthera regularis  is a hemi-parasitic shrub. It is known for treating various health ailments. The aim of this study was to evaluate the antimicrobial activity, toxicity, and chemical characterization of the leaf extracts of  P regularis  collected from the  Schinus molle  host plant in Ethiopia. The antimicrobial properties of crude extracts obtained with chloroform, ethyl acetate, methanol, and water solvents were assayed against  Escherichia coli ,  Staphylococcus aureus , and  Pseudomonas aeruginosa.  The methanol extract significantly inhibited the growth of  S. aureus, E. coli  and  P. aeruginosa  were resistant to any of these solvent extracts. The methanol extract was tested at 175, 550, and 2000 mg/kg body weight doses in white mice and did not reveal any toxicity. The LC-MS qTOF analysis detected flavonoids, phenolic acids, and alkaloids in the crude methanol extract. Further study is needed to investigate the effectiveness of these compounds against  S. aureus .

Biological and phytochemical characterization of Phragmanthera regularis (Loranthaceae) from Ethiopia