English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Three new feruloyl glucuronopyranosyl glycerols, 1- O - α -D-(2′-feruloyl) glucuronopyranosyl glycerol ( 1 ), 1- O - α -D-(3′-feruloyl) glucuronopyranosyl glycerol ( 2 ), and 1- O - α -D-(4′-feruloyl) glucuronopyranosyl glycerol ( 3 ) were isolated and purified from the capitulum of  Eriocaulon buergerianum  Koern. Their structures were identified by spectroscopic and chemical methods. Molecular docking study showed that  1  is a potential inhibitor of TGF- β 1 receptor. Bioassay results revealed that  1  exhibited strong inhibitory activity against the TGF- β -induced expression of α-smooth muscle actin ( α -SMA) and fibronectin in human hepatic stellate LX-2 cells. The results in this study indicated that the new feruloyl glucuronopyranosyl glycerol  1  has preventive and therapeutic potentials against hepatic fibrosis.

Three new feruloyl glucuronopyranosyl glycerols from Eriocaulon buergerianum with their anti-fibrotic effects on hepatic stellate cells