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Two new sesquiterpenoids, sarglanoids G and H ( 1  and  2 ), together with two known analogues ( 3 – 4 ) were isolated from the roots of  Sarcandra glabra . Compound  2  was a rare elemene-type sesquiterpenoid with a furan ring fragment, which is mostly lactone ring in its analogues. The structures of new compounds were determined on the basis of extensive spectroscopic methods including HR-ESI-MS, 1D and 2D NMR, and the absolute configuration of  1  was established by ECD calculations. Their anti-inflammatory activities were also evaluated.

Two new sesquiterpenoids from the roots of Sarcandra glabra