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Two new phenylpropanoids ( 1  and  2 ) and one new isoflavone glycoside ( 3 ), along with nine known compounds ( 4  −  12 ), were isolated from the pod of  Ceratonia siliqua  L. Their chemical structures were elucidated based on extensive spectroscopic analyses (1 D and 2 D NMR, UV, IR, and HRESIMS) and compared with the literature data. In addition, all isolated compounds were evaluated  in vitro  for inhibitory activity against acetylcholinesterase (AChE). Compounds  4 ,  5 , and  12  showed inhibitory activity against acetylcholinesterase (AChE) with IC 50  values ranging from 15.0 to 50.2 μM.

Novel phenylpropanoids and isoflavone glycoside are isolated and identified from the carob pods ( Ceratonia siliqua L.)