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A simple synthetic approach has been developed for the enantioselective total synthesis of (+)-Sedridine, (-)-Allosedridine and their analogs such as (+)- N - Methyl Sedridine and (-)- N -Methylallosedridine. The synthesis was achieved by using commercially available starting materials  via  Maruoka-Keck allylation, Wacker oxidation, and CBS reduction. The synthetic root provides a good diastereomeric ratio and high yields.

Enantioselective synthesis of (+)-Sedridine, (-)-Allosedridine and their N -Methyl analogs via Maruoka - Keck allylation and CBS reduction