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A new sesquiterpene (Prosoterpene,  1 ) and eleven reported compounds ( 2 – 12 ) of several classes, such as flavonoids, alkaloids, phenolic acids, and long-chain alcohols, were isolated from the BuOH extract of  Prosopis africana  (Guill. &amp; Perr.) Taub. Compounds  2 – 10  were reported for the first time from this plant. Isomers  11  and  12  were separated for the first time. Extensive spectroscopic techniques and literature comparisons were used to characterise their structures. Furthermore, compounds  3 ,  5 – 8 , and  10 – 12  were performed for anti-glycation and cytotoxicity activities. Compound  3  (quercetin-3- O - α -L-rhamnoside) exhibited moderate anti-glycation activity. All tested compounds were non-cytotoxic against MCF-7 (breast cancer), NCI-H460 (lung cancer), Hela (cervical cancer), and BJ (normal human fibroblast) cell lines.

A new sesquiterpene, prosoterpene, from Prosopis africana (Guill. & Perr.) Taub