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Calea pinnatifida  (R. Br.) Less. is a plant of Brazilian folk medicine. We evaluated the influence of environmental factors on the chemical profile of  C. pinnatifida  collected during the winter season.  C. pinnatifida  leaves, alongside soil samples, were collected from two sites of different altitude. Plant samples were sequentially extracted, while soil samples were subject to compositional analysis. Plant extracts were compared using HPTLC-UV, using chemometric analyses to compare samplings harvested at both altitudes. Two marker metabolites, calein A ( 1 ) and acetylportentol ( 2 ), were isolated from samples collected at the respective altitudes. The differing metabolic profiles observed may be a result of the influence of environmental factors.

Chemical fingerprinting of the Brazilian medicinal plant Calea pinnatifida (R. Br.) Less. (Asteraceae) collected at different altitudes