English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

A new glycoside, recurvataside ( 1 ) and six known compounds, quinovic acid ( 2 ), quinovic acid 28- O - β -D-glucopyranosyl ester ( 3 ), 3- O - β -D-glucopyranosylquinovic acid ( 4 ), 3- O - β -D-glucopyranosylquinovic acid 28- O - β -D-glucopyranosyl ester ( 5 ), pomolic acid ( 6 ), and ursolic acid ( 7 ) were isolated from aerial parts of  Mussaenda recurvata . The structure of compound  1  was identified from its spectroscopic data and by comparison with the literature. Recurvataside represents the first occurrence of  δ -oleanolic acid saponin bearing two D-glucose units at C-3 and C-28 in nature. This is the first time  δ -oleanane-type saponin reported in the genus  Mussaenda . Compounds  1-7  were evaluated the cytotoxicity against two cancer cell lines MCF-7 and HepG2. Among them, only compound  7  exhibited moderate activity against MCF-7 and HepG2 cell lines with IC 50  value of 16.97 ± 1.55 and 20.28 ± 1.00 μM, respectively. Compounds  1 – 7  were also tested for their inhibitory NO production in LPS-stimulated RAW264.7 cells. Compounds  3 ,  5 , and  7  showed significant reduction of nitrite accumulation in LPS-stimulated RAW 264.7 cells with the IC 50  values of 8.81 ± 0.48, 13.42 ± 0.84, and 18.37 ± 0.67 μM, respectively.

Recurvataside, a new saponin from aerial parts of Mussaenda recurvata