English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

The aerial parts of  Nepeta teucriifolia  Willd. were extracted with the solvents of different polarities. The antiproliferative activities of the extracts were evaluated against rat brain tumor (C6) and human cervix carcinoma (HeLa) cell lines. The phytochemical screening of the extracts was performed with TOF-LC/MS. The CH 2 Cl 2  and EtOAc extracts showed considerable antiproliferative activities against HeLa cells at higher concentration (250 µg mL −1 ). The CH 2 Cl 2  extract was found more active than the others on both cells. The phytochemical studies of the active extract led to the isolation of three new iridoids, teucriifolian A-C ( 1–3 ). The structure elucidations of the new compounds were performed using HPLC-TOF/MS, 1D and 2D NMR techniques. The compounds  1–3  were evaluated in terms of their antiproliferative activities against HeLa and C6 cells, respectively. The results indicated that only  2  had moderate antiproliferative activity against HeLa cells at 250 µg mL −1 .

Three new iridoids from the aerial parts of Nepeta teucriifolia Willd. and antiproliferative activities of extracts