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The endophytic fungus  Periconia  sp. TJ403-rc01 (Dematiaceae) isolated from the leaves of  Rosa chinensis  Jacq. (Rosaceae) was cultivated on rice medium and chemically investigated, affording two new lanostane-type triterpenoids, namely pericinones A and B ( 1  and  2 ). Their structures were determined mainly by 1 D and 2 D NMR and HRESIMS data. Notably, it is the first report of lanostane-type triterpenoids from species of  Periconia . Compounds  1  and  2  showed moderate anti-inflammatory activity against the NO production with IC 50  values of 24.12 ± 0.73 and 11.38 ± 1.56  μ M, respectively.

Two new lanostane-type triterpenoids from the fungus Periconia sp. TJ403-rc01