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A new ingol diterpenoid, namely 3-de- O -acetyleuphornan R ( 1 ), along with two known analogues, euphornans E ( 2 ) and N ( 3 ) were isolated from the seeds of  Euphorbia marginata  Pursh. The structure of  1  was elucidated by extensive  1 H NMR,  13 C NMR, HSQC, HMBC, and  1 H- 1 H COSY, and HR-MS spectroscopic analyses.

A new ingol diterpenoid from the seeds of Euphorbia marginata Pursh