English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Plus monthly

Global: Zendy Tools annual

Global: Zendy Tools monthly

Global: Zendy Free Plan

Three glycosylated stilbenes ( 1 – 3 ), two anthraquinones ( 4 ,  5 ), one lignan ( 6 ), five tannins ( 7 – 11 ), two amino acids ( 12 ,  13 ), and one auronol ( 14 ) were isolated from the root of  Ampelopsis japonica . All compounds, except for  4 ,  6 , and  11  were obtained from this species for the first time. Compounds  6 – 9  could notably inhibit ROS generations in HaCaT keratinocyte cells with IC 50  values of 5.28, 4.83, 0.87, and 1.66 μM, respectively. Compounds  8 – 10  showed potent DPPH free radical scavenging effects with IC 50  values of 14.37, 16.08, and 12.11 μM, individually. In anti-melanogenesis assay, only  8  and  9  could decrease 7.93% and 11.66% melanin contents induced by α-MSH in B16F10 melanoma cells at 40 μM and moderately inhibit tyrosinase activities. By far, galloylhamameloses  8  and  9  were found to exhibit both antioxidant and anti-melanogenesis properties that could be further developed as cosmeceutical agents for skin disorders.

Characterization of chemical constituents with their antioxidant and anti-melanogenesis activities from the roots of Ampelopsis japonica