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Phytochemical investigation of the fruit of  Acronychia pedunculata  (L.) Miq. led to the isolation of a new prenylated flavone, acroflavone A ( 1 ), together with eight known compounds ( 2 – 9 ). Their structures were elucidated by thorough analysis of mass spectrometric and NMR spectroscopic data. The isolated compounds were evaluated against several bacterial strains. Three known compounds ( 3 – 5 ) demonstrated antibacterial activities. Among them, acrovestone ( 5 ) proved equally or more potent than chloramphenicol against three out of the four strains tested.

Acroflavone A, a new prenylated flavone from the fruit of Acronychia pedunculata (L.) Miq