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Two new flavanoids fissistiganoids A and B ( 1  and  2 ), together with two known pterocarpans derivatives ( 3  and  4 ), were isolated from the stems of  Fissistigma tungfangense . The structures of these compounds were elucidated using comprehensive spectroscopic methods. The absolute configurations of fissistiganoids A and B ( 1  and  2 ) were determined by comparing their ECD spectra with quantum-mechanics ECD calculations. The inhibitory activities of all compounds against three cancer cell lines HeLa, MCF-7 and A549 were evaluated. Compounds  1–4  showed moderate inhibitory effects on HeLa, MCF-7 and A549 cells with IC 50  values ranging from 12.5 to 42.3  μ M.

Fissistiganoids A and B: two new flavonoids from the Fissistigma tungfangense