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Two new cytochalasins, deacetyl-19 -epi- cytochalasin P1 ( 1 ), deacetyl-19,20-epoxycytochalasin D ( 2 ) were isolated from the endophytic fungus  Diaporthe  sp. RJ-47, along with four known compounds deacetyl-5,6-dihydro-7-oxo-19,20-epoxycytochalasin C ( 3 ), 19,20-epoxycytochalasin Q ( 4 ), 19,20-epoxycytochalasin C ( 5 ) and deacetyl-19,20-epoxy cytochalasin C ( 6 ). Their structures were unambiguously elucidated on the basis of the comprehensive analysis of extensive spectroscopic data. The antimicrobial effects of these compounds were evaluated.

Six 19,20-epoxycytochalasans from endophytic Diaporthe sp. RJ-47