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The chemical composition of the methanol extract obtained from  Araucaria cunninghamii  Sweet. bark was determined by GC-MS analysis with its antioxidant and antibacterial potential, for the first time. A total of 73 compounds were identified and the extract was strongly characterised by Viridiflorene; Androstan-17-one, 3-ethyl-3-hydroxy-, (5α)-; 8-Isopropenyl-1,3,3,7-tetramethyl-bicyclo[5.1.0]oct-5-en-2-one; 3,6,9-Triethyl-3,6,9-trimethyl-tetracyclo[6.1.0.0 ∼ 2,4∼.0 ∼ 5,7∼]-nonane; Longifolenaldehyde; (-)-Caryophyllen-(I1); 2-hydroxymethyl-5-furfural; Methyl commate B; 3-Ethyl-3-hydroxyandrostan-17-one; 3-Hydroxybenzoic acid as the main components (55.39%).  A. cunninghamii  extract presents IC 50 , 53.52 µg/mL and 65.29 µg/mL using DPPH and H 2 O 2  scavenging assay, respectively. The antibacterial activity of the extract was evaluated for eight microorganisms showed that the extract had a remarkable inhibitory potential with a mean zone diameter of inhibition ranging from 09 to 21 mm. The methanol extract of  A. cunninghamii  showed significant antibacterial activity against  X. campestris  (21 mm, ZOI) with MIC and MBC values 15.6 and 31.25 µg/mL, respectively.

Phytochemical constituents, antimicrobial and antioxidant activities of Kumaun Himalayan Hoop Pine bark extract