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The aim of this study was to evaluate the chemical composition and the larvicidal activity of  Brunfelsia uniflora  leaf and flower extracts against  Aedes aegypti  larvae. Twenty-four compounds were found in the leaf extract, and the major compounds were phytol (23.1%), 9,12,15-octadecatrienoic acid, ethyl ester (21.3%), and hexadecanoic acid, ethyl ester (12.8%). In the flower extract, twenty-four compounds were also identified and the major compounds were  α -amyrin (35.7%),  β -amyrin (16.4%), and ( EE )-geranyl linalool (9.6%) by gas chromatography coupled to mass spectrometry. The larvicidal activity was evaluated by larval immersion test. The lethal concentrations (LC) obtained from leaf extract were LC 50  = 4.89 and LC 99.9  = 11.14 mg/mL and from flower extract were LC 50  = 3.82 and LC 99.9  = 11.03 mg/mL, and the positive control presented LC 50  = 0.40 and LC 99.9  = 1.14 mg/mL. Thus,  B. uniflora  extracts are promising alternatives to control  A. aegypti  larvae.

Larvicidal activity of Brunfelsia uniflora extracts on Aedes aegypti larvae