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From the leaves of  Ricinus communis  Linn., one new alkaloid, named ricicomin A ( 1 ) together with three known ones, ricinine ( 2 ),  N -demethylricinine ( 3 ) and 4-[2-formyl-5-(methoxymethyl)-1H-pyrrol-1-yl]butanoic acid ( 4 ) were justified by repeated chromatographic methods. Their structures were determined by comprehensive IR, HR-ESI-MS and NMR analyses. Compound  4  was identified for the first time from the genus  Ricinus . DFT-NMR chemical shift calculations and subsequent DP4+ probability methods were applied to confirm the chemical structure of  1 . Compounds  1–3  did not display cytotoxic effect against three human cancer cell lines (MCF-7, HepG2 and HeLa) using SRB assay.

Ricicomin A, a new alkaloid from the leaves of Ricinus communis Linn