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The primary objective was to describe the incidence, symptoms, clinical signs, and time of onset of neonatal pneumothorax in Örebro County during 2011–2017. Secondary objectives were to describe risk factors, diagnostic procedures, treatments, and mortality and to compare preterm with term/post-term neonates. This retrospective population-based descriptive study included all neonates born in Örebro County during 2011–2017 and admitted to the neonatal intensive care unit at Örebro University Hospital at age &lt;28 days with an x-ray verified diagnosis of “Pneumothorax originating in the perinatal period” in their medical record. Seventy-five neonates matched the inclusion criteria. The incidence of neonatal pneumothorax in Örebro County during the study period was 3.1 (95% CI: 2.5–3.8) per 1000 live births. All neonates were &lt;48 h at debut of respiratory symptoms and the most common symptom was tachypnea. Twelve (16%) received invasive treatment. The mortality rate was 2 (3%), none due to pneumothorax. The incidence of 3.1 per 1000 live births was relatively high, but the frequency of invasive treatment and mortality was low, indicating a high proportion of mild pneumothoraces. The lack of patients aged &gt;48 h indicates that most neonatal pneumothoraces now occur very early in life.

Neonatal pneumothorax: symptoms, signs and timing of onset in the post-surfactant era