English (United Kingdom)

https://curated-unify.zendy.io/wp-json/zendy-region/v1/featured_content/oa?rat=en

https://curated-unify.zendy.io/wp-json/zendy-region/v1/highlighted_journal/

Global: Zendy Plus annual

Presents the access of premium content as premium feature

Premium Content

Presents the keyphrase highlighting as premium feature

Keyphrase Highlighting

Presents the summarisation as premium feature

Summarisation

Insights

Presents the pdf analysis as premium feature

PDF Analysis

Presents the zaia usage as premium feature

ZAIA

Global: Zendy Tools annual

Global: Zendy Free Plan

Global: Zendy Tools monthly

Global: Zendy Plus monthly

Background: Limb sparing surgery has replaced the amputation surgery in the treatment of limb sarcomas. Recurrent or persistent disease constitutes a major problem. Local symptoms such as agonizing pain, fractures, tumor fungation, inability to walk and inability to maintain daily activities, further impair the patient’s quality of life. In this clinical set-up palliative amputation should be considered. Methods: Eighteen patients with soft-tissue or bone sarcomas and three patients with metastatic carcinoma underwent palliative major amputation. Hemipelvectomy was performed in three patients, hip disarticulation in 10 patients, knee disarticulation or below-knee amputation in three patients, shoulder disarticulation in one patient, forequarter amputation in four patients. Results: Local control of the disease and pain, and improvement of the performance status were observed in 19 evaluable patients. The mobility was restored in 15 patients with lower limb surgery. The median survival following the procedure was 9 months. There was only one case of immediate post-operative death. Severe phantom pain was not reported by any of the patients. Quality of life was reported to be improved by two-thirds of the patients. Conclusion: Our data point to the fact that palliative amputation surgery is feasible, not associated with increased mortality, and is worth-performing in low-performance status cancer patients with locally advanced disease. Local symptoms and signs were controlled, and quality of life was restored. In our opinion, pain alone does constitute an indication for palliative major amputation, especially if it is accompanied by pain-related limb dysfunction or low performance status.

16th Annual Meeting of the European Musculo-Skeletal Oncology Society & 4th Symposium of the EMSOS Nurse Group, 7–9 May 2003, Budapest: Abstracts