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The development of transdiagnostic cognitive-behavioural therapy (T-CBT) is a promising avenue for the treatment of anxiety disorders. This study aimed at evaluating the feasibility and effectiveness of a group T-CBT, developed by practising clinicians, for patients with principal and comorbid anxiety disorders in a pragmatic quasi-experimental trial. Clinician-rated and self-rated measures were used to assess principal (anxiety) and secondary (depression, daily functioning, quality of life) outcomes. Forty-two participants from an anxiety outpatient clinic of a mental health hospital with at least one primary anxiety disorder took part in the study. The intervention consisted of 8 to 10 weekly group T-CBT sessions of 120 minutes. Among the 42 participants recruited, 37 completed baseline measures. Attrition was high (35%) as only 24 participants completed the treatment as intended. Significant improvements were observed on anxiety, depression, and daily functioning as well as physical and psychological quality of life measures. Gains were maintained up to three months after the end of treatment. Findings support the effectiveness of a group T-CBT for anxiety disorders in an outpatient clinic. However, feasibility was only partially supported highlighting the need for further research on the transportability of group T-CBT in to clinical practice. What is already known about this topic:(1) Transdiagnostic group CBT is an effective treatment for anxiety disorders.(2) Few studies have examined the effectiveness of transdiagnostic group CBT in naturalistic settings.(3) Few studies have examined the effectiveness of treatments as implemented by clinicians in routine clinical practice. (1) Transdiagnostic group CBT is an effective treatment for anxiety disorders. (2) Few studies have examined the effectiveness of transdiagnostic group CBT in naturalistic settings. (3) Few studies have examined the effectiveness of treatments as implemented by clinicians in routine clinical practice. What this paper adds:(1) Eight to ten sessions of transdiagnostic group CBT developed by practising clinicians seemed sufficient in improving anxiety and depressive symptoms, daily functioning, and quality of life in patients from an outpatient anxiety disorders clinic in a hospital setting.(2) Patients that completed treatment reported significantly more impairment in daily functioning before treatment than participants who dropped out.(3) High attrition rates suggest that organisational factors need to be considered while implementing evidence-based treatments into routine clinical practice. (1) Eight to ten sessions of transdiagnostic group CBT developed by practising clinicians seemed sufficient in improving anxiety and depressive symptoms, daily functioning, and quality of life in patients from an outpatient anxiety disorders clinic in a hospital setting. (2) Patients that completed treatment reported significantly more impairment in daily functioning before treatment than participants who dropped out. (3) High attrition rates suggest that organisational factors need to be considered while implementing evidence-based treatments into routine clinical practice.

Integrated group treatment for anxiety disorders: a transdiagnostic effectiveness and feasibility study in a mental health hospital setting