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Taste is a crucial organoleptic characteristic that determines whether a substance will be accepted for delivery through the mouth. However, the vast majority of medications have an unpleasant taste. Drugs with a bitter taste are often depicted using a variety of flavouring compounds to increase patient acceptance and compliance. Human panellists are the principal means of assessing the flavour of medication ingredients and formulations. Due to the toxicity of medications and subjectivity of taste panellists, as well as issues with hiring taste panellists and panel upkeep when working with unpleasant items, the use of sensory panellists in the industry is particularly challenging and troublesome. Furthermore, tests cannot be conducted on compounds that have not received FDA approval. As a result, the analytical taste-sensing multichannel sensory system known as the electronic tongue (also known as the artificial tongue or e-tongue) helps in reducing the number of samples that are ought to be assessed by trained sensory panels and also when the sample to be tasted is injurious or harmful for the concerned person. Therefore, e-tongue has advantages like lowering reliance on human panels. The working theory, the sensors used, and the pharmaceutical and food applications are covered, along with the major software used, difficulties, and future scope are also highlighted.

pharmaceutical development and technology

The electronic tongue: an advanced taste-sensing multichannel sensory tool with global selectivity for application in the pharmaceutical and food industry