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Polychlorinated biphenyls (PCBs) are banned toxic contaminants according to the Stockholm Convention of persistent pollutants (2001); however, they continue to be prevalent in the environment of Pakistan. The current study evaluates the risk to infants exposed to PCBs in breast milk from urban centers of Pakistan. The ∑14PCB concentrations ranged from ND to 118.36 ng/g lipid weight (l.w.) with a mean of 11.76. ± 4.88 ng/g l.w. These levels are greater than concentrations previously reported from Asia. The quantified PCB profile was also significantly ( p  &lt; .05) related to the age of the mother while a negative correlation was observed with diet pattern (−0.26), fat content (−0.63), number of children (−0.185), and lactation (−0.19). There were significant differences among test locations with greater bioaccumulation observed in breast milk collected from urbanized Rawalpindi compared to less urbanized Jhang. The calculated estimated daily intakes of dioxin-like PCBs for infants were considerably higher than the recommended daily intake suggested by different organizations. The calculated hazard ratio (HR &gt; 1) indicates health risks to infants in selected study regions.

Signature tracing of PCBs congeners in breastmilk of mothers living in selected urban centers of Pakistan